Pingueculae and Pterygia in Motorcycle Policemen.

p53 expression and relation to human papillomavirus infection in pingueculae, pterygia, and limbal tumors.

BACKGROUND The tumor suppressor gene p53 is expressed without apoptosis in the limbal basal stem cells of all pterygia and limbal tumors and most pingueculae from which these growths seem to originate. Oncogenic human papillomaviruses (HPVs) have been found in pterygia and limbal tumors, and HPV and p53 overexpression commonly coexist in oropharyngeal and penile carcinomas. OBJECTIVE To searc...

Telomerase activity and p53 expression in pterygia.

PURPOSE To investigate tolomerase activity and p53 expression in pterygial tissue. METHODS Pterygia tissue was obtained during excisional surgery fr om 35 eyes of 35 patients, and superior bulbar conjunctival tissue from the same eye was also sampled as control when possible. Fluorescence telomeric repeat amplification protocol was used to measure telomerase activity in whole pterygium sample...

The science of pterygia.

Pterygium is an ocular surface disease of humans attributed to chronic ultraviolet-B exposure. Clinically, the condition involves invasive centripetal growth with associated inflammation and neovascularisation. Previous clinical studies focused primarily on the clinical characteristics and surgical management of pterygia and, because of this, the pathogenesis of pterygia remains incompletely un...

Publication bias and journals as policemen.

Increasing lymphatic microvessel density in primary pterygia.

OBJECTIVE To examine lymphatic microvessel density (LMVD) in primary pterygia. METHODS We included tissue samples from 88 excised primary (including 34 grade 1, 28 grade 2, and 26 grade 3) pterygia and from 7 nasal epibulbar conjunctivae segments used as control samples. Sections from each pterygium were immunostained with CD31 and lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1) m...